Scientific journal
Scientific Review. Biological science
ISSN 2500-3399
ПИ №ФС77-57454

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INFLUENCE OF BIOLOGICALLY ACTIVE SUBSTANCES AND VITAMINS B2 BACTERIAL GROWTH STRAIN CORYNEBACTERIUM GLUTAMICUM B-11167 IN LIQUID MEDIUM

Sirotin A.A. 1 Ospischeva N.V. 1 Bondarenko V.V. 1 Rezun A.P. 1
1 FSA EIHPE «Belgorod National Research University»
Microbiological synthesis of amino acids , including essential - lysine , one of the best producers is Corynebacterium glutamicum Efficiency of biosynthesis depends on genetic features of a strain, conditions of cultivation, such as temperatures, pH, structure of a nutrient medium, vitamins and BAV (growth factors. Dynamics of growth of culture of a strain of C. glutamicum B-11167 is investigated at cultivation on a liquid nutrient medium of LB with use of various BAV and B2 vitamin. The positive dynamics of growth of the strain in the culture fluid containing vitamin В2 at 0,2 mg/ml. It is revealed that indoleacetic acid at its addition in concentration 0, 00005 mg/ml suppresses growth of culture by 5% in comparison with control. Influence of addition of arachidonic acid in concentration 0,0003 gave suppression of growth of cages of culture for 8%. Influence of indolebutyric acid isn’t expressed and corresponded to culture growth in control.