Scientific journal
Scientific Review. Biological science
ISSN 2500-3399
ПИ №ФС77-57454

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THE FUNCTIONAL STATE OF THE HINDLIMB MUSCLES OF CHRONIC SPINAL CORD-INJURED RATS

Baltina T.V. 1 Abyazovа L.M. 1 Yafarova G.G. 1 Khazieva A.R. 1
1 Kazan (Volga) Federal University. Kazan
High frequency ofspinal cord injury is combined with the complexity of traumatic spinal cord pathogenesis. The absence of adequate treatment and rehabilitation methods of patients with severe consequences of spinal cord injury makes the issue go beyond the purely medical aspects. The aim of the research was to assess the state of tonic and phasic leg muscles of the rat being in condition of traumatic spinal cord injury. The assessment of the peripheral part of the neuromuscular system of rats was being made using electromyography methods. Motor response (M-response) of the muscle was being registered. The maximum amplitude, duration, thresholdand latent period of the response were being determined. The experiments were performed in compliance with the bioethical standards. Decrease of the maximum amplitude, threshold and duration of the M-response, increase of the latent period in all studied muscles is observed during the chronic phase after the spinal cord injury. 5 months after the spinal cord injury recovery of M-response parameters is observed. This indicates the processes of regeneration and preparation of muscle fibers tothe post-traumatic phase. The exception was the soleus muscle that is significantly different from the rest in terms of muscle fiber composition. It is concluded that the degree of sensitivity to the spinal cord injury of different leg muscles is not the same: maximum depth changes is observed in postural-tonic flexor - soleus muscle.