science-review.ru
Scientific journal
Scientific Review. Biological science
ISSN 2500-3399
ПИ №ФС77-57454
ISSN 2500-3399
ПИ №ФС77-57454
STRUCTURAL AND FUNCTIONAL ORGANIZATION OF AMYGDALA IN RATS, SHOWING DIFFERENT STRATEGIES OF BEHAVIOR WHICH ASSOCIATED WITH GENETICALLY CAUSED CHANGES IN THE EXPRESSION OF ISOFORMS OF RECEPTOR D2
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The aim of this work was the analysis of structural and quantitative characteristics of Amygdala and content of dopamine in rats with genotypes А1/А1 and А2/А2 on the locus Taq 1 A DRD2. Morphometric analysis of Amygdala showed that its area do not differ in rats with genotypes А1/А1 and А2/А2, but reveal a highly significant increase of specific area of basolateral group of structures of Amygdala and major index of the relative weight of brain in rats with genotype A2/A2. Chromatographic analysis of Amygdala’s tissue showed that in the Amygdala of rats with genotype A1/A1 contains more dopamine compared with rats with genotype A2/A2. Also revealed that rats with genotype A2/A2 has no differences in the content of dopamine between corticomedial and basolateral groups while in rats with genotype A1/A1 such differences are present. This can lead to the changing relationship between these groups.