Scientific journal
Scientific Review. Biological science
ISSN 2500-3399
ПИ №ФС77-57454

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THE INFLUENCE OF ZEOLITES ON THE STATE OF PLASMOCOAGULASE IN EXPERIMENTAL ANIMALS AFTER REVERSIBLE OCCLUSION

Zinoveva A.V. 1 Nikulina E.G. 1
1 Khanty-Mansiysk State Medical Academy
Hemostasis efforts to date have been largely aimed at combating the effects of increasing trombinogeneza - in clinical practice are widely used various forms of heparin, which have a direct anticoagulant effect, and inhibitors of the synthesis of vitamin K-dependent coagulation factors. For substances, antioxidant properties are proven and are zeolites - natural modulators selective entero donor-sorbent interactions between their own structure and mineral complex biochemical conveyor gastrointestinal tract. Antioxidant activity of zeolites due to the ability to capture free radicals. Experimental and clinical observations have shown that zeolites, along with antioxidant properties, and have a more wide range of effects of a different kind - immunomodulatory, regenerative, antitoxic, desensitizing, hepatoprotective. The aim of this work is to study the effect of zeolites on the state of plasma-coagulation in experimental animals after reversible occlusion. These results indicate that the introduction of the zeolite does not increase, but rather decreases the anticoagulant potential of the vascular wall and the ability to distinguish inhibitors of platelet activation in response to stress impact.