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Scientific journal
Scientific Review. Biological science
ISSN 2500-3399
ПИ №ФС77-57454
ISSN 2500-3399
ПИ №ФС77-57454
PECULIARITIES OF INFLUENCE OF CARBOXYHEMOGLOBIN ON THE PERFORMANCE OF THE OXYGEN REGIME OF BLOOD IN SMOKERS AND NON-SMOKERS BOYS
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Significant contribution to the deterioration in the oxygen functions of the body when tobacco smoking contributes intake of moonooksida carbon monoxide (CO), which has significantly higher compared with the oxygen affinity to 71 72 hemoglobin (Hb). CO, partially blocking the transport processes of oxygen due to the formation сarboхуhemoglobin (COHb) is not capable to carry oxygen significantly reduces its delivery tissues. In this connection it is interesting to study the links content COHb with parameters reflecting the state of oxygen homeostasis - blood oxygen saturation (satO2) and an indicator of the affinity of Hb for O2 p50 (half-saturation of oxyhemoglobin O2). This paper presents the results of a study of these relations by regression analysis in non-smokers and smokers. It turned out that the dependence on the content of COHb satO2 smokers boys differs from the regression line in non-smokers - the lack of the ascending part of the curve and a distinct decrease in oxygen saturation with increasing concentration of COHb. At the same time, the growth of smokers COHb values accompanied by increased quantities of p50, i.e. with increasing concentration of COHb increases deoxygenation Hb, and therefore the diffusion of oxygen to the tissues. This fact can be considered as one of the mechanisms of adaptation of the organism to oxygen imbalance smokers. It is important to note that non-smokers identified as negative processes and adaptive reactions occur at relatively low concentrations of COHb, which confirms the known facts of the harm of passive smoke.