Scientific journal
Scientific Review. Biological science
ISSN 2500-3399
ПИ №ФС77-57454

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EFFECT OF LONG EMOTIONAL PAIN STRESS ON ACTIVITY OF CARBOXYPEPTIDASE H IN TISSUES FEMALE RATS AT DIFFERENT STAGES ESTROUS CYCLE

Vishnyakova Z.S. 1
1 Penzensky State University
The article deals with the problem of effect of a single continuous emotional pain stress on the activity of carboxypeptidase H (CPH) in the hypothalamus, pituitary gland, striatum, adrenal glands and gonads of female albino rats at different stages of the estrous cycle. It was found that acute stress caused a reduction in activity of CPH in the pituitary, hypothalamus and striatum in the stages of proestrus and estrus. However diestrus increased in these parts of the enzyme activity. Opposite changes CPH activity at different stages of the cycle under stress due to the different resistance of animals to the effects of stress factors during the estrous cycle The stress increased the enzymatic activity in the adrenal gland. It is suggested that the CPH is involved in the determination of the differences in the response to stress, in adaptation and resilience to stressful effects at different stages of the estrous cycle.