Lyukhanov M.P. 1
Korotkevich O.S. 1
Sebezhko O.I. 1
Yudin N.S. 2
1 Novosibirsk state agrarian university
2 Institute of Cytology and Genetics
The paper presents frequencies of TNF-α -824 A/G alleles and genotypes and associations of single nucleotide polymorphism with biochemistry parameters of blood and milk productivity indices in Red Steppe cattle. The frequencies of genotypes A/A, A/G and G/G were respectively 0.260, 0.460 and 0.280. A and G allele frequencies were 0.490 and 0.510. The association of TNF-α-824 A/G single nucleotide polymorphism with milk productivity indices was revealed. Homozygous for the TNF-α A/A cows had the yield and speed of lactation higher than the animals of other genotypes. Upward trend in the total protein content was observed in the homozygous A/A individuals. The regularities in the association of TNF-α gene polymorphism with zootechnical indices are true for the concerned population of Red Steppe cattle bred under the certain environmental conditions, the level of productivity and the current time period of breeding