Scientific journal
Scientific Review. Biological science
ISSN 2500-3399
ПИ №ФС77-57454

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THE STUDY LITOLITIC AND DIURETIC ACTIVITY OF SUNFLOWER ANNUAL ROOT (HELIANTHUS ANNUUS) EXTRACTS

Melik-Guseynov V.V. 1 Gerasimenko S.V. 1 Timchenko L.D. 2 Piskov S.I. 2
1 Filial of Volgograd State Medical University
2 North-Caucasian Federal University
Conducted experience of lithol urinary stones in vitro under the influence of root sunflower extracts. Studied diuretic and litolitic the action of various extracts the root of sunflower in the conditions of experimental model of urolithiasis animals. The results show that when oxalate urolithiasis in white rats root sunflower annual had litolitic activity, accompanied by a reduction in the size of microliths and reduction of crystalluria. The mechanism lethalities actions are not caused by the dissolution of calcium deposits. It is possibly connected with the content of substances in the root of sunflower that inhibit the growth of crystals of calcium oxalate, and also with active diuretic action. It prevents aggregation of crystals in renal tubule.