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Scientific journal
Scientific Review. Biological science
ISSN 2500-3399
ПИ №ФС77-57454
ISSN 2500-3399
ПИ №ФС77-57454
ADDITIONAL CRITERION FOR ASSESSING THE DEGREE OF TISSUE HYPOXIA IN PATIENTS WITH PNEUMONIA
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Hypoxia is a universal regulator of energy processes in normal and important cause of metabolic disorders cells. As a typical pathological process hypoxia accompanies many diseases, including pneumonia, in which it is due to a violation of respiratory function (ERF) [4]. The purpose of this study was to assess the diagnostic significance of analyzing the age composition of red blood cells in peripheral blood and managers determine the level of fetal hemoglobin (FetHb) with pneumonia, and establish relationships with the studied parameters of the traditional criteria of functioning oxygen transport system (ITS). The paper found that the ventilation violations ERF, manifested in a significant decrease in pO2 values (from 80.5 mmHg in the control group to 67.8 mm Hg in patients with pneumonia), offset by a significant increase content FetHb (5 4% vs. 2.9% in controls) having high affinity for oxygen and which is therefore redundant overcome by hypoxia. Found in patients with pneumonia change the degree of acidity is the stability of erythrocytes, obviously, trigger the gain response of molecular genetic mechanism during adaptation to hypoxia and patients can be treated along with FetHb marker of hypoxia. The leading role of these mechanisms in maintaining oxygen homeostasis confirmed by the results of the factor analysis.