Scientific journal
Scientific Review. Biological science
ISSN 2500-3399
ПИ №ФС77-57454

Personal portfolio

RESEARCH OF INFLUENCE OF ORANGE-RED COMPONENT (ΛMAX=626 NM) IN MODEL SUNLIGHT SPECTRUM ON THE VIABILITY OF MAMMALIAN CELL IN VITRO

Fakhranurova L.I. 1 Selezneva I.I. 1 Manokhin А.А. 2 Davidova G.A. 1 Khramov R.N. 1
1 Institute of Theoretical and Experimental Biophysics of RAS
2 Institute of Cell Biophysics of RAS
We have done the study of the effect of orange-red component (λmax = 626 nm) in the solar spectrum, obtained through the screens consisting of luminophore materials, on the viability of mammalian cells (fibroblasts 3T3 clone NIH; epithelial cell line HEp-2 cells and rabbit cornea line SIRC) in vitro. Our study showed that the presence of even small-intensity fluorescent additional components (λmax = 626nm) in the spectrum of sunlight leads to stimulation of intracellular processes and improve the regenerative abilities, resulting in an increase in cell viability according to the MTT assay. This opens up prospects of using light-converting material to protect the eye tissues from photodamage and prevention of degenerative and age-related changes in the macular area of ther etina.